Significance of the Difference between the Areas under Two Independent ROC Curves
For two ROC curves derived from independent samples, this calculator will assess the significance of the difference between the areas that lie under the curves.

To proceed, enter the indicated data in the text boxes highlighted in yellow, then click the «Calculate» botton.


Sample A
Sample B
 number of actually negative cases 


number of actually positive cases 


area under curve 


standard error 


difference: areaA—areaB 

standard error of the difference 



P: non-directional (two-tailed) 

P: directional (one-tailed) 

   Reset        Calculate 

Reference:
Hanley JA, McNeil BJ. The meaning and use of the area under a Receiver Operating Characteristic (ROC) curve. Radiology, 1982, 143, 29-36.


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